Posts tagged "Microbiome"
Thoughts on bioinformatics, data analysis, and research
4 posts
2025
4 posts
What on Earth Is the Microbiome? (Explained as If We Were Having a Beer) 🍺
You’re not just you: you’re an ecosystem. Over a beer, we explore what the microbiome is, what it does for you, and why losing the balance can mess with your health.
Letting AI pick the right differential abundance method, taxon by taxon
Microbiome data are messy, and no single differential abundance method wins everywhere. Here I explore how AI could learn, taxon by taxon, which method is most reliable using modern benchmarks and simulated/semi-simulated datasets.
Protein Binding Pockets: Structure, Dynamics and AI-Based Prediction
A deep dive into what binding pockets are, how they shape enzyme function, and how modern AI and structure prediction tools let us map them at scale.
BEAUT: Using AI to Reveal Hidden Bile Acid Enzymes in the Gut Microbiome
A Cell paper introduces BEAUT, an AI pipeline that predicts over 600,000 bile-acid–modifying enzymes in the gut microbiome and uncovers a new bile acid that reshapes microbe–microbe interactions.
